Suyash Bhatt and Emily Masterson, et al., have taken wireless to the next level. Through their published paper Wireless in vivo recording of cortical activity by an ion-sensitive field effect transistor they were able to validate a new approach for an integrated circuit for wireless in situ recording of brain electrophysiology.
Wireless brain technologies are empowering basic neuroscience and clinical neurology by offering new platforms that minimize invasiveness and refine possibilities during electrophysiological recording and stimulation. Despite their advantages, most systems require on-board power supply and sizeable transmission circuitry, enforcing a lower bound for miniaturization. Designing new minimalistic architectures that can efficiently sense neurophysiological events will open the door to standalone microscale sensors and minimally invasive delivery of multiple sensors. Here we present a circuit for sensing ionic fluctuations in the brain by an ion-sensitive field effect transistor that detunes a single radiofrequency resonator in parallel. We establish sensitivity of the sensor
by electromagnetic analysis and quantify response to ionic fluctuations in vitro.
Read more here: https://www.sciencedirect.com/science/article/pii/S0925400523002642
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